Structural highlights
Publication Abstract from PubMed
The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) triggers the release of large amounts of interleukin-4 from human blood basophils, thus presumably playing an immunomodulatory role during schistosome infection. IPSE/alpha-1 was crystallized and a native X-ray data set was collected to 1.66 A resolution from a single crystal at 100 K using synchrotron radiation. The crystal belonged to space group P6(1) or P6(5), with one molecule per asymmetric unit.
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1).,Mayerhofer H, Schramm G, Hatzopoulos GN, Mueller-Dieckmann C, Haas H, Mueller-Dieckmann J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jun 1;65(Pt 6):594-6. doi:, 10.1107/S1744309109015899. Epub 2009 May 22. PMID:19478439[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Mayerhofer H, Schramm G, Hatzopoulos GN, Mueller-Dieckmann C, Haas H, Mueller-Dieckmann J. Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1). Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jun 1;65(Pt 6):594-6. doi:, 10.1107/S1744309109015899. Epub 2009 May 22. PMID:19478439 doi:http://dx.doi.org/10.1107/S1744309109015899
