Ribozyme

From Proteopedia

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Ribozyme (RZ) is an RNA molecule which catalyzes a chemical reaction^[1].

• Glucosamine-6-phosphate activated RZ (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites.
  
• Leadzyme is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see Student Projects for UMass Chemistry 423 Spring 2012-10.
  
• Hairpin RZ and hammerhead RZ are named based on their shape^[2].
  
• Group I intron catalyzes its own selfish splicing^[3].

Articles in Proteopedia concerning ribozymes include:

• Azoarcus group I intron
• Kink-turn motif
• Ribosome
• The Large Ribosomal Subunit
• Hairpin Ribozyme
• Human CPEB3 ribozyme's P4 domain

To view automatically seeded indices concerning ribozymes, see:

• Ribozyme
• Catalytic RNA
• GlmS
• Hammerhead
• Hairpin
• Hepatitis delta virus
• Twister
• Twister sister
• Hatchet
• Pistol
• Group I intron
• Varkud satellite

3D Structures of Ribozymes

Updated on 22-August-2016

References

1. ↑ Tang J, Breaker RR. Rational design of allosteric ribozymes. Chem Biol. 1997 Jun;4(6):453-9. PMID:9224568
2. ↑ Amarzguioui M, Prydz H. Hammerhead ribozyme design and application. Cell Mol Life Sci. 1998 Nov;54(11):1175-202. PMID:9849614 doi:http://dx.doi.org/10.1007/s000180050247
3. ↑ Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990;59:543-68. PMID:2197983 doi:http://dx.doi.org/10.1146/annurev.bi.59.070190.002551