Sphingomyelinase

From Proteopedia

Revision as of 08:47, 31 August 2016 by Michal Harel (Talk | contribs)

(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)

Sphingomyelinase (SMase) is a hydrolase involved in sphingolipid metabolism. It catalyzes the breakdown of sphingomyelin (SM) to phosphocholine and ceramide^[1]. The SMase is classified into 5 types according to their pH dependence and cation dependence.

3D structures of sphingomyelinase

Updated on 31-August-2016

3rlh, 3rlg – SMase D (mutant) – Loxosceles intermedia
1xx1, 2f9r – SMase I – Loxosceles laeta
1zwx – SMase C – Listeria ivanovii
2ddr, 2dds, 2ddt – BcSMase + cation – Bacillus cereus
2uyr – BcSMase (mutant)
3wcx – SMase C – Streptomyces griseocarneus