Villin
From Proteopedia
- Villin (VIL) is an actin-binding protein. It contains gelsolin-like domains in its N-terminal and a helical headpiece which binds actin[1].
- Supervillin (SVIL) contains numerous gelsolin-like domains in its C-terminal and interacts with actin.
- Advillin (AVIL) is another actin-binding protein in the gelsolin superfamily which is expressed in the peripheral sensory neurons.
- Cytovillin (CVIL) or ezrin or villin-2 serves as intermediate between plasma membrane and actin cytoskeleton.
3D Structures of Villin
Updated on 25-June-2015
References
- ↑ Friederich E, Vancompernolle K, Louvard D, Vandekerckhove J. Villin function in the organization of the actin cytoskeleton. Correlation of in vivo effects to its biochemical activities in vitro. J Biol Chem. 1999 Sep 17;274(38):26751-60. PMID:10480879
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Michal Harel, Alexander Berchansky, David Canner, Jaime Prilusky, Joel L. Sussman
