WD repeat-containing protein

From Proteopedia

3D Structures of WD-repeat protein 5

Updated on 14-December-2016

2gnq, 2h68, 2h14, 2h9l – hWDR5 – human
3mxx, 3n0d, 3n0e – hWDR5 (mutant)
3smr, 3ur4, 4ia9, 4qqe, 4ql1 – hWDR5 + piperazine derivative
2cnx, 2co0, 2h6k, 2h6n, 2h6q, 2h13, 2h9m, 2h9n, 2h9p, 2g99, 2g9a, 2o9k, 3psl, 4a7j – hWDR5 + histone H3 peptide
3eg6, 3emh – hWDR5 + MLL1 peptide
4gm3, 4gm8, 4gm9, 4gmb – hWDR5 + peptide inhibitor
2xl2, 2xl3 – hWDR5 + retinoblastoma-binding protein 5 peptide
4o45 – hWDR5 + influenza NS1 C-terminal
4cy1 – hWDR5 + KAT8 regulatory NSL complex subunit 1+2 peptides
4cy2 – hWDR5 + KAT8 regulatory NSL complex subunit 1 peptide
4y7r – hWDR5 + Myc MbIIIb peptide
3uvk, 3uvl, 3uvm, 3uvn, 3uvo, 4erq, 4ery, 4es0, 4esg, 4ewr – hWDR5 + MLL peptide
4erz – hWDR5 + MLL4
3p4f – hWDR5 + retinoblastoma-binding protein 5 peptide + MLL peptide

References

1. ↑ Gan Q, Thiebaud P, Theze N, Jin L, Xu G, Grant P, Owens GK. WD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2. J Biol Chem. 2011 Jun 17;286(24):21853-64. doi: 10.1074/jbc.M111.233098. Epub, 2011 Apr 28. PMID:21531708 doi:http://dx.doi.org/10.1074/jbc.M111.233098
2. ↑ Tullio-Pelet A, Salomon R, Hadj-Rabia S, Mugnier C, de Laet MH, Chaouachi B, Bakiri F, Brottier P, Cattolico L, Penet C, Begeot M, Naville D, Nicolino M, Chaussain JL, Weissenbach J, Munnich A, Lyonnet S. Mutant WD-repeat protein in triple-A syndrome. Nat Genet. 2000 Nov;26(3):332-5. PMID:11062474 doi:http://dx.doi.org/10.1038/81642
3. ↑ Schuetz A, Allali-Hassani A, Martin F, Loppnau P, Vedadi M, Bochkarev A, Plotnikov AN, Arrowsmith CH, Min J. Structural basis for molecular recognition and presentation of histone H3 by WDR5. EMBO J. 2006 Sep 20;25(18):4245-52. Epub 2006 Aug 31. PMID:16946699