1r3m

From Proteopedia

Revision as of 11:46, 20 March 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:1r3m.gif


PDB ID 1r3m

Drag the structure with the mouse to rotate
, resolution 2.2Å
Ligands:
Activity: Pancreatic ribonuclease, with EC number 3.1.27.5
Coordinates: save as pdb, mmCIF, xml



Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease


Overview

Bovine seminal ribonuclease is a unique case of protein dimorphism, since it exists in two dimeric forms, with different biological and kinetic behavior, which interconvert into one another through three-dimensional swapping. Here we report the crystal structure, at 2.2 A resolution, of the unswapped form of bovine seminal ribonuclease. Besides completing the structural definition of bovine seminal ribonuclease conformational dimorphism, this study provides the structural basis to explain the dependence of the enzyme cooperative effects on its swapping state.

About this Structure

1R3M is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Crystal structure of the dimeric unswapped form of bovine seminal ribonuclease., Berisio R, Sica F, De Lorenzo C, Di Fiore A, Piccoli R, Zagari A, Mazzarella L, FEBS Lett. 2003 Nov 6;554(1-2):105-10. PMID:14596923

Page seeded by OCA on Thu Mar 20 13:46:23 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1r3m"
Personal tools