Agglutinin

From Proteopedia

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spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Agglutinins (AGG) are sugar-binding lectins which cause particles to change from fluid state to thickened-mass state. Agglutinin isolectin or wheat germ agglutinin is a plant protein that binds specifically to sugars expressed by human gastrointestinal epithelial and immune cells[1]. Disease Cold agglutinin disease is a disorder affecting patients with autoimmune anemia[2]. Structural highlights

3D Structures of lactoferrin

Updated on 02-January-2017

References

1. ↑ Dalla Pellegrina C, Perbellini O, Scupoli MT, Tomelleri C, Zanetti C, Zoccatelli G, Fusi M, Peruffo A, Rizzi C, Chignola R. Effects of wheat germ agglutinin on human gastrointestinal epithelium: insights from an experimental model of immune/epithelial cell interaction. Toxicol Appl Pharmacol. 2009 Jun 1;237(2):146-53. doi:, 10.1016/j.taap.2009.03.012. Epub 2009 Mar 28. PMID:19332085 doi:http://dx.doi.org/10.1016/j.taap.2009.03.012
2. ↑ Swiecicki PL, Hegerova LT, Gertz MA. Cold agglutinin disease. Blood. 2013 Aug 15;122(7):1114-21. doi: 10.1182/blood-2013-02-474437. Epub 2013, Jun 11. PMID:23757733 doi:http://dx.doi.org/10.1182/blood-2013-02-474437