Structural highlights
2xvy is a 1 chain structure with sequence from Desvh. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , , , |
| Activity: | Sirohydrochlorin cobaltochelatase, with EC number 4.99.1.3 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[CBIKP_DESVH] Catalyzes the insertion of Co(2+) into sirohydrochlorin. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. Its periplasmic location means that it cannot participate in cobalamin biosynthesis and its genomic environment suggests it is likely to be associated with a heme or metal transport system.[1]
References
- ↑ Lobo SA, Brindley AA, Romao CV, Leech HK, Warren MJ, Saraiva LM. Two distinct roles for two functional cobaltochelatases (CbiK) in Desulfovibrio vulgaris hildenborough. Biochemistry. 2008 May 27;47(21):5851-7. doi: 10.1021/bi800342c. Epub 2008 May 6. PMID:18457416 doi:http://dx.doi.org/10.1021/bi800342c
