Function
Urease accessory protein (Ure) is a Ni-containing urea hydrolase involved in nitrogen recycling from arginine, ureide and purines. Ure proteins are involved in urease activation by the transfer of Ni into the protein[1].
- UreE - see Molecular Playground/UreE.
- UreF - modulates the activation process of urease by eliminating the binding of Ni irons to noncarbamylated protein[2].
- UreI - probably facilitates nickel incorporation.
Structural highlights
The Ni+2 ion coordinates six ligands which include 3 His residues belonging to the two monomers, Glu from a symmetry-related monomer, water molecule and an unidentified ligand which may be a His from an unobserved part of the chain[3]
