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Contents 1 Major Prion Protein 2 Function 3 Disease 4 Relevance 5 Structural Highlights 6 References

Major Prion Protein

spinqualitylabelsall models Major Prion Protein (PDB entry 5l6r) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Structure The image shown is the average structure produced by NMR constraints.

Major Prion Protein

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Function

The normal function of the prion protein is as a transport protein in Homo Sapiens. In it's mutated state the prion protein functions in the development of amyloid disease (misfiled proteins that stick together forming fibrils).

Disease

The disease associated with a mutated Prion protein is Spongiform Ecephalopathies. The common prion disease in humans is known as Creutzfeldt-Jakob disease.

Relevance

Structural Highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

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References