Severin

From Proteopedia

Revision as of 09:52, 28 August 2016 by Michal Harel (Talk | contribs)
Jump to: navigation, search
Crystal Structure of Human Severin, 3fg6
Crystal Structure of Human Severin, 3fg6

Template:STRUCTURE 1svy

Severin is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins[1]. It is named Adseverin and Scinderin as well.


3D Structures of Severin

3fg6 – Adseverin C-terminal – human
1svy – DdSeverin domain 2 – Dictyostelium discoideum
1svq, 1svr - DdSeverin domain 2 - NMR

References

  1. ↑ Summerscales J, Dawson JF. Probing Dictyostelium severin structure and function by cross linking to actin. Biochem Cell Biol. 2004 Apr;82(2):343-50. PMID:15060630 doi:http://dx.doi.org/10.1139/o04-002

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Jaime Prilusky

Retrieved from "http://52.214.119.220/wiki/index.php/Severin"
Personal tools