Tissue factor

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Structure of human tissue factor (dark green) complex with coagulation factor VIIa heavy chain (red) and light chain (aqua) and Ca+2 ion (green) (PDB code 2aer).

Drag the structure with the mouse to rotate

3D structures of tissue factor

Updated on 14-September-2016

References

  1. ↑ Chen VM, Hogg PJ. Encryption and decryption of tissue factor. J Thromb Haemost. 2013 Jun;11 Suppl 1:277-84. doi: 10.1111/jth.12228. PMID:23809131 doi:http://dx.doi.org/10.1111/jth.12228
  2. ↑ Poon RT, Lau CP, Ho JW, Yu WC, Fan ST, Wong J. Tissue factor expression correlates with tumor angiogenesis and invasiveness in human hepatocellular carcinoma. Clin Cancer Res. 2003 Nov 1;9(14):5339-45. PMID:14614019
  3. ↑ Pawlinski R, Tencati M, Holscher T, Pedersen B, Voet T, Tilley RE, Marynen P, Mackman N. Role of cardiac myocyte tissue factor in heart hemostasis. J Thromb Haemost. 2007 Aug;5(8):1693-700. PMID:17663739 doi:http://dx.doi.org/10.1111/j.1538-7836.2007.02649.x

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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