NEDD8

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NEDD8 is a ubiquitin-like protein in humans. It facilitates ubiquitin conjugation. It participates in the recruitment of E2 to the ubiquitin ligase complex. NEDD8 modifies the cullin subunits (CUL) of SCF ubiquitin E3 ligase^[1]. In yeast the protein is called Rub1.

3D Structures of NEDD8

Updated on 05-May-2016

References

↑ Chiba T, Tanaka K. Cullin-based ubiquitin ligase and its control by NEDD8-conjugating system. Curr Protein Pept Sci. 2004 Jun;5(3):177-84. PMID:15180522