Sm-like protein

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Template:STRUCTURE 1m8v


Sm-like proteins are ring-shaped oligomers of 6-7 members which show nucleic acid-binding activity[1]. For details on Sm1 of Archaeoglobus fulgidus see AF-Sm1. For details on the human protein see Lsm.

3D Structures of Sm-like protein

Updated on 30-August-2016

1i81, 1jri, 1mgq, 1jbm – MtSm – Methanothermobacter thermautotrophicus
1loj – MtSm + UMP
1i8f, 1m5q, 1lnx – Sm – Pyrobaculum aerophilum
1i4k – AfSm1 – Archaeoglobus fulgidus
1i5l – AfSm1 + RNA
1ljo – AfSm2
1m8v – PaSm1 + RNA – Pyrococcus abyssii
1h64 – PaSm
2fb7 – LSm14 – zebra fish – NMR
3bw1 – yLSm3 - yeast
4c8q – yLSm1 + LSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + DNA topoisomerase 2-associated protein
3pgg – LSm5 – Cryptosporidium parvum
3swn, 4emk – LSm5 + LSm6 + LSm7 – fission yeast
4c92, 4m75 – yLSm1 + LSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7
4c8q – yLSm1 + LSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + DNA topoisomerase 2-associated protein
4m77, 4m78 – yLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8
4m7a – yLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 + U6 SnRNA
4m7d – yLSm2 + LSm3 + LSm4 + LSm5 + LSm6 + LSm7 + LSm8 + RNA

References

  1. Valentin-Hansen P, Eriksen M, Udesen C. The bacterial Sm-like protein Hfq: a key player in RNA transactions. Mol Microbiol. 2004 Mar;51(6):1525-33. PMID:15009882

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Michal Harel

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