Structural highlights
1ka0 is a 1 chain structure with sequence from Atcc 18824. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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Ligands: | , |
Related: | 1qgx, 1k9y, 1k9z, 1ka1 |
Gene: | HAL2 (ATCC 18824) |
Activity: | 3'(2'),5'-bisphosphate nucleotidase, with EC number 3.1.3.7 |
Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum |
Function
[MET22_YEAST] Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Regulates the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. Involved in salt tolerance. Confers resistance to lithium.
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.