Structural highlights
1n6x is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , |
| Related: | 1n6y, 1n7a, 1n7b |
| Activity: | Trypsin, with EC number 3.4.21.4 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum |
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The use of third generation synchrotron sources has led to renewed concern about the effect of ionizing radiation on crystalline biological samples. In general, the problem is seen as one to be avoided. However, in this paper, it is shown that, far from being a hindrance to successful structure determination, radiation damage provides an opportunity for phasing macromolecular structures. This is successfully demonstrated for both a protein and an oligonucleotide, by way of which complete models were built automatically. The possibility that, through the exploitation of radiation damage, the phase problem could become less of a barrier to macromolecular crystal structure determination is discussed.
Specific radiation damage can be used to solve macromolecular crystal structures.,Ravelli RB, Leiros HK, Pan B, Caffrey M, McSweeney S Structure. 2003 Feb;11(2):217-24. PMID:12575941[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Ravelli RB, Leiros HK, Pan B, Caffrey M, McSweeney S. Specific radiation damage can be used to solve macromolecular crystal structures. Structure. 2003 Feb;11(2):217-24. PMID:12575941
