1ztl
From Proteopedia
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, resolution 2.60Å | |||||||
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Ligands: | and | ||||||
Gene: | F11 (Homo sapiens) | ||||||
Activity: | Coagulation factor XIa, with EC number 3.4.21.27 | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with N-[4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-{6-oxo-5-[(quinolin-8-ylmethyl)-amino]-2-m-tolyl-6H-pyrimidin-1-yl}-acetamide
Disease
Known diseases associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]
About this Structure
1ZTL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 15:39:39 2008
Categories: Coagulation factor XIa | Homo sapiens | Single protein | Abdel-Meguid, S S. | Babine, R. | Bibbins, F. | Jin, L. | Meyers, H. | Nagafuji, P. | Quinn, J. | Rynkiewicz, M. | Strickler, J E. | 737 | SO4 | Fxia | Inhibitor