2aaq

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Image:2aaq.gif


PDB ID 2aaq

Drag the structure with the mouse to rotate
, resolution 2.60Å
Ligands: , , , , , and
Gene: hGR (Homo sapiens)
Activity: Glutathione-disulfide reductase, with EC number 1.8.1.7
Coordinates: save as pdb, mmCIF, xml



Crystal Structure Analysis of the human Glutahione Reductase, complexed with GoPI


Disease

Known diseases associated with this structure: Hemolytic anemia due to glutathione reductase deficiency OMIM:[138300], Mental retardation, autosomal recessive, 6 OMIM:[138244]

About this Structure

2AAQ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases., Urig S, Fritz-Wolf K, Reau R, Herold-Mende C, Toth K, Davioud-Charvet E, Becker K, Angew Chem Int Ed Engl. 2006 Mar 13;45(12):1881-6. PMID:16493712

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