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Unusual sequence numbering
From Proteopedia
The numbering of protein and nucleic acid sequences is arbitrary in structure files from the World Wide Protein Data Bank (PDB). Here are some examples. These PDB entries are not shown here. To explore these, the links below will display them in FirstGlance in Jmol (link with arrow) or in Proteopedia (link in parentheses).
Not Monotonic
Rarely, sequence numbers do not increase monotonically from N to C terminus. An example[1] is 4zwj (4zwj). In this chimeric protein, chain A is numbered 1002-1161 continuing 1-326 continuing 2012-2361. That is, there are sudden jumps in numbering of consecutive amino acids: 1161 to 1, and 326 to 2012.
References
- ↑ Thanks to Rachel Kramer Green of RCSB.org for this example.
