5i7c

Structural highlights

Function

[CNN_DROME] Core component of the centrosome throughout spermatogenesis. May participate in mitotic spindle assembly and the mechanics of morphogenesis through an interaction with microtubules, either directly or indirectly. Is a target of several homeotic genes.^{[1] [2]}

References

1. ↑ Li K, Kaufman TC. The homeotic target gene centrosomin encodes an essential centrosomal component. Cell. 1996 May 17;85(4):585-96. PMID:8653793
2. ↑ Li K, Xu EY, Cecil JK, Turner FR, Megraw TL, Kaufman TC. Drosophila centrosomin protein is required for male meiosis and assembly of the flagellar axoneme. J Cell Biol. 1998 Apr 20;141(2):455-67. PMID:9548723