Microtubule-associated serine/threonine kinase

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spinqualitylabelsall models Human Microtubule_associated serine/threonine kinase 1 PDZ domain complex with imidazole and ethylene glycol (PDB code 3ps4) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Microtubule_associated serine/threonine kinase (MAST) belongs to a family of proteins which contain a serine/threonine kinase domain and a PDZ domain. MAST1 associates with the cytoskeleton and can bind through its PDZ domain both β-2-synthrophin and neuronal nitric oxide synthase. MAST2 regulates lipopolysaccharide-induced IL-12 synthesis.

3D Structures of microtubule-associated serine/threonine kinase

Updated on 20-December-2017 {{#tree:id=OrganizedByTopic|openlevels=0|

• Microtubule_associated serine/threonine kinase 1

• • 3ps4 – MAST1 PDZ domain 965-1057 – human
    
  • 2m9x – MAST1 residues 187-287 – NMR
    

• Microtubule_associated serine/threonine kinase 2

• • 2kqf, 2kyl – hMAST2 PDZ domain + glycoprotein C-terminal - NMR
    

• Microtubule_associated serine/threonine kinase 3

• • 2w7r – hMAST3 PDZ domain
    

• Microtubule_associated serine/threonine kinase 4

• • 3khf – hMAST4 PDZ domain
    

• Microtubule_associated serine/threonine kinase-like or Greatwall

• • 5loh – hMAST3-L kinase domain
    

References