2fk6

From Proteopedia

Revision as of 14:53, 20 March 2008 by OCA (Talk | contribs)
Jump to: navigation, search
Image:2fk6.gif


PDB ID 2fk6

Drag the structure with the mouse to rotate
, resolution 2.90Å
Ligands: , and
Gene: RNZ (Bacillus subtilis)
Activity: Ribonuclease Z, with EC number 3.1.26.11
Coordinates: save as pdb, mmCIF, xml



Crystal Structure of RNAse Z/tRNA(Thr) complex


Overview

The highly conserved ribonuclease RNase Z catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Here we present the structure of the complex between Bacillus subtilis RNase Z and tRNA(Thr), the first structure of a ribonucleolytic processing enzyme bound to tRNA. Binding of tRNA to RNase Z causes conformational changes in both partners to promote reorganization of the catalytic site and tRNA cleavage.

About this Structure

2FK6 is a Protein complex structure of sequences from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

Structure of the ubiquitous 3' processing enzyme RNase Z bound to transfer RNA., Li de la Sierra-Gallay I, Mathy N, Pellegrini O, Condon C, Nat Struct Mol Biol. 2006 Apr;13(4):376-7. Epub 2006 Mar 5. PMID:16518398

Page seeded by OCA on Thu Mar 20 16:53:23 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2fk6"
Personal tools