Alpha-lytic protease

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spinqualitylabelsall models Structure of alpha-lytic protease protease domain (green) and pro domain (magenta) complex with benzenesulfonyl fluoride (PDB entry 3pro) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Alpha-lytic protease (ALP) is a bacterial serine protease of the chymotrypsin family. ALP is a two-domain enzyme. One domain is a large pro region (residues 1-199) that catalyzes the folding of the protease. The second domain is the protease domain (residues 200-397).[1] . (PDB entry 3pro).[2]

3D Structures of alpha-lytic protease

Updated on 12-March-2018

References

1. ↑ Bone R, Frank D, Kettner CA, Agard DA. Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry. 1989 Sep 19;28(19):7600-9. PMID:2611204
2. ↑ Sauter NK, Mau T, Rader SD, Agard DA. Structure of alpha-lytic protease complexed with its pro region. Nat Struct Biol. 1998 Nov;5(11):945-50. PMID:9808037 doi:http://dx.doi.org/10.1038/2919