2l9c

Structural highlights

Function

[MUP20_MOUSE] Male pheromone which stimulates female sexual attraction to male urinary scent and promotes a strong learned attraction to the airborne urinary odor of an individual male. Promotes male aggressive behavior. Binds most of the male pheromone, 2-sec-butyl-4,5-dihydrothiazole, in urine.^{[1] [2] [3]}

References

1. ↑ Armstrong SD, Robertson DH, Cheetham SA, Hurst JL, Beynon RJ. Structural and functional differences in isoforms of mouse major urinary proteins: a male-specific protein that preferentially binds a male pheromone. Biochem J. 2005 Oct 15;391(Pt 2):343-50. PMID:15934926 doi:http://dx.doi.org/10.1042/BJ20050404
2. ↑ Chamero P, Marton TF, Logan DW, Flanagan K, Cruz JR, Saghatelian A, Cravatt BF, Stowers L. Identification of protein pheromones that promote aggressive behaviour. Nature. 2007 Dec 6;450(7171):899-902. PMID:18064011 doi:http://dx.doi.org/10.1038/nature05997
3. ↑ Roberts SA, Simpson DM, Armstrong SD, Davidson AJ, Robertson DH, McLean L, Beynon RJ, Hurst JL. Darcin: a male pheromone that stimulates female memory and sexual attraction to an individual male's odour. BMC Biol. 2010 Jun 3;8:75. doi: 10.1186/1741-7007-8-75. PMID:20525243 doi:http://dx.doi.org/10.1186/1741-7007-8-75