Structural highlights
Function
[FRIL_HORSE] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
We report the preparation of organometallic Pd(allyl) dinuclear complexes in protein cages of apo-Fr by reactions with [Pd(allyl)Cl]2 (allyl = eta3-C3H5). One of the dinuclear complexes is converted to a trinuclear complex by replacing a Pd-coordinated His residue to an Ala residue. These results suggest that multinuclear metal complexes with various coordination structures could be prepared by the deletion or introduction of His, Cys, and Glu at appropriate positions on protein surface.
Control of the coordination structure of organometallic palladium complexes in an apo-ferritin cage.,Abe S, Niemeyer J, Abe M, Takezawa Y, Ueno T, Hikage T, Erker G, Watanabe Y J Am Chem Soc. 2008 Aug 13;130(32):10512-4. Epub 2008 Jul 18. PMID:18636721[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Abe S, Niemeyer J, Abe M, Takezawa Y, Ueno T, Hikage T, Erker G, Watanabe Y. Control of the coordination structure of organometallic palladium complexes in an apo-ferritin cage. J Am Chem Soc. 2008 Aug 13;130(32):10512-4. Epub 2008 Jul 18. PMID:18636721 doi:10.1021/ja802463a
