Choline O-acetyltransferase

Revision as of 13:42, 14 December 2015 by Alexander Berchansky (Talk | contribs)

Human choline O-acetyltransferase complex with choline (PDB entry 2fy3)

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3D Structures of choline O-acetyltransferase

Updated on 14-December-2015

1q6x, 1t1u – ChaT – rat

2fy2 – hChaT – human

2fy3 – hChaT + choline

2fy4 – hChaT + CoA

2fy5 – hChaT + CoA derivative

↑ Oda Y. Choline acetyltransferase: the structure, distribution and pathologic changes in the central nervous system. Pathol Int. 1999 Nov;49(11):921-37. PMID:10594838
↑ Kim AR, Rylett RJ, Shilton BH. Substrate binding and catalytic mechanism of human choline acetyltransferase. Biochemistry. 2006 Dec 12;45(49):14621-31. PMID:17144655 doi:10.1021/bi061536l