Epithelial discoidin domain-containing receptor

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3D structures of epithelial discoidin domain-containing receptor 1

Updated on 27-December-2018

5bvk – hDDR1 kinase domain 564-913 – human
3zos, 4bkj, 4bkj – hDDR1 kinase domain + cancer drug
6few – hDDR1 kinase domain + alport syndrome drug
6fex, 6fil, 6fim, 6fin, 6fio, 6fiq – hDDR1 kinase domain (mutant) + alport syndrome drug
4ckr, 5bvn, 5bvo, 5bvw, 5fdp, 5fdx, 6brj, 6gwr – hDDR1 kinase domain + inhibitor
4ag4 – hDDR1 29-367 domain + antibody

References

  1. ↑ Toy KA, Valiathan RR, Nunez F, Kidwell KM, Gonzalez ME, Fridman R, Kleer CG. Tyrosine kinase discoidin domain receptors DDR1 and DDR2 are coordinately deregulated in triple-negative breast cancer. Breast Cancer Res Treat. 2015 Feb;150(1):9-18. doi: 10.1007/s10549-015-3285-7., Epub 2015 Feb 10. PMID:25667101 doi:http://dx.doi.org/10.1007/s10549-015-3285-7

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Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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