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Introduction
The 1ki4 protein is the thymidine kinase from Herpes simplex virus type I complexed with 5-bromothienyldeoxyuridine.
The Herpes simplex virus type I also called HSV1 cause highly contagious infections worldwide. In most cases, it is orofacial herpes but there is also a small proportion of genital infections.
The thymidine kinase is located in human cells and virus cells like in Herpes simplex virus. In the human cells, it exists two forms called TK1 and TK2.
This protein is a phosphotransferase enzyme that catalyses the reaction:
Deoxythymidine + ATP Deoxythymidine monophosphate + ADP
Function
Disease
Relevance
Structural highlights
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
