From Proteopedia
proteopedia link proteopedia link Crystal structure of the mutant F100A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
Structural highlights
3nqa is a 2 chain structure with sequence from "methanobacterium_thermoautotrophicus"_(sic)_zeikus_and_wolfe_1972 "methanobacterium thermoautotrophicus" (sic) zeikus and wolfe 1972 . Full crystallographic information is available from OCA . For a guided tour on the structure components use FirstGlance . Ligands: Related: 3g18 , 3nq6 , 3nq7 , 3nqc , 3nqd , 3nqe , 3nqf , 3nqg , 3nqm Gene: pyrF, MTH_129 ("Methanobacterium thermoautotrophicus" (sic) Zeikus and Wolfe 1972 ) Activity: Orotidine-5'-phosphate decarboxylase , with EC number 4.1.1.23 Resources: FirstGlance , OCA , PDBe , RCSB , PDBsum , ProSAT
Function
[PYRF_METTH ] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
