Structural highlights
Function
[IRPL1_MOUSE] May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in presynaptic and postsynaptic differentiation and dendritic spine formation in neurons.[1]
References
- ↑ Yoshida T, Yasumura M, Uemura T, Lee SJ, Ra M, Taguchi R, Iwakura Y, Mishina M. IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase delta. J Neurosci. 2011 Sep 21;31(38):13485-99. doi: 10.1523/JNEUROSCI.2136-11.2011. PMID:21940441 doi:http://dx.doi.org/10.1523/JNEUROSCI.2136-11.2011
