Structural highlights
4a46 is a 4 chain structure with sequence from Aphanocapsa sp. (strain n-1). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , |
| Related: | 1sb6, 2xmt, 2xmv, 2xmm, 2xmk, 2xmj, 2xmu, 4a47, 4a48 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Publication Abstract from PubMed
The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(II)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins.
Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains.,Badarau A, Basle A, Firbank SJ, Dennison C Chem Commun (Camb). 2013 Sep 21;49(73):8000-2. doi: 10.1039/c3cc42709a. Epub 2013, Aug 7. PMID:23926594[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Badarau A, Basle A, Firbank SJ, Dennison C. Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains. Chem Commun (Camb). 2013 Sep 21;49(73):8000-2. doi: 10.1039/c3cc42709a. Epub 2013, Aug 7. PMID:23926594 doi:http://dx.doi.org/10.1039/c3cc42709a
