Structural highlights
Publication Abstract from PubMed
NirD is part of the nitrite reductase complex NirBD that catalyses the reduction of nitrite to NH(3) in nitrate assimilation and anaerobic respiration. The crystal structure analysis of NirD from Mycobacterium tuberculosisshows a double?beta-sandwich fold. NirD is related in three-dimensional structure and sequence to the Rieske proteins, however it does not contain any Fe-S cluster or other cofactors that might be involved in electron transfer. A cysteine residue at the protein surface, conserved in NirD homologues lacking the iron- sulfur cluster might be important for the interaction with NirB, and possibly stabilize one the Fe-S centers in this subunit. Proteins 2012. (c) 2012 Wiley Periodicals, Inc.
Crystal structure of NirD, the small subunit of the nitrite reductase NirBD from Mycobacterium tuberculosis, at 2.0 A resolution.,Izumi A, Schnell R, Schneider G Proteins. 2012 Sep 10. doi: 10.1002/prot.24177. PMID:22965870[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Izumi A, Schnell R, Schneider G. Crystal structure of NirD, the small subunit of the nitrite reductase NirBD from Mycobacterium tuberculosis, at 2.0 A resolution. Proteins. 2012 Sep 10. doi: 10.1002/prot.24177. PMID:22965870 doi:http://dx.doi.org/10.1002/prot.24177
