From Proteopedia
proteopedia linkproteopedia linkRapamycin is an immuno-suppressant and anticancer drug. It acts by binding the the mTORC1 protein complex, a kinase that regulates cell growth and metabolism. In the future, it might also be used in treatment of type 2 diabetes[1].
Structure
References
- ↑ https://doi.org/10.3389/fphar.2016.00395
- ↑ Marz AM, Fabian AK, Kozany C, Bracher A, Hausch F. Large FK506-binding Proteins Shape the Pharmacology of Rapamycin. Mol Cell Biol. 2013 Jan 28. PMID:23358420 doi:http://dx.doi.org/10.1128/MCB.00678-12