Structural highlights
Function
[MLAC_ECOLI] Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the periplasmic space and deliver it to the MlaFEDB complex at the inner membrane.[1]
References
- ↑ Malinverni JC, Silhavy TJ. An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane. Proc Natl Acad Sci U S A. 2009 May 12;106(19):8009-14. doi:, 10.1073/pnas.0903229106. Epub 2009 Apr 21. PMID:19383799 doi:http://dx.doi.org/10.1073/pnas.0903229106
