1mh1
From Proteopedia
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| , resolution 1.38Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | RHO (Homo sapiens) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
SMALL G-PROTEIN
Contents |
Overview
The crystal structure of human rac1, a member of the rho family of small G-proteins, complexed with the non-hydrolysable GTP analogue, guanosine-5'-(beta gamma-imino)triphosphate (GMPPNP), has been determined by X-ray analysis at a resolution of 1.38 A. Comparison with the structure of H-ras indicates that rac1 has an extra alpha-helical domain that is characteristic of the rho G proteins, and may be involved in the signalling pathway of this family.
Disease
Known disease associated with this structure: Night blindness, congenital stationery, rhodopsin-related OMIM:[180380], Retinitis pigmentosa, autosomal recessive OMIM:[180380], Retinitis pigmentosa-4, autosomal dominant OMIM:[180380]
About this Structure
1MH1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue., Hirshberg M, Stockley RW, Dodson G, Webb MR, Nat Struct Biol. 1997 Feb;4(2):147-52. PMID:9033596
Page seeded by OCA on Sun Mar 30 22:15:56 2008
