Nudix hydrolase
From Proteopedia
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3D structures of Nudix hydrolase
Updated on 12-November-2019
3mgm – hNDX 16 - human
5vy2, 5w6z, 5wji – hNDX 16 (mutant)
6b09 – hNDX 16 (mutant) + DIDPR
[5w6x]] – hNDX 16 (mutant) + ADP-ribose
2xsq – hNDX 16 + IMP
2b0v, 3cng - NDX - Nitrosomonas europaea
1k2e, 1jrk, 1k26 - NDX (mutant) - Pyrobaculum aerophilum
1sjy, 1soi, 2w4e - DrNDX - Deinococcus radiodurans
1su2 - DrNDX + ATP
1sz3 - DrNDX + GNP
3fcm, 3f6a - NDX - Clostridium perfringens
3qsj - NDX - Alicyclobacillus acidocaldarius
3r03 - NDX - Rhodospirillum rubrum
2azw, 2fml - NDX - Enterococcus faecalis
2b06, 2pqv - NDX - Streptococcus pneumoniae
3exq - NDX - Lactobacillus brevis
3i9x - NDX - Listeria innocua
3id9, 3smd - NDX - Bacillus thuringiensis
4dyw - NDX - Burkholderia pseudomallei
6dby, 5wwd – AtNDX 1 - Arabidopsis thaliana
5wy6 – AtNDX 1 (mutant)
6fl4 – AtNDX 1 + 8-oxo-DGTP
6dbz – AtNDX 1 + isopentenyl phosphate
5gp0 – AtNDX 1 + geranyl diphosphate
4zb3 – AtNDX 7
4zbp – AtNDX 7 + AMPCPR
5gg5 – MsMuTT 1 – Mycobacterium smegmatis
5ggc, 5ggd – MsMuTT 1 + phosphate
5xd3, 5xd4 – MsMuTT 1 + ATP
5gg6 – MsMuTT 1 + 8-oxo-DGTP
5ggb – MsMuTT 1 + 8-oxo-DGDP
5gg7, 5gg8, 5gg9, 5gga – MsMuTT 1 + 8-oxo-DGTP + 8-oxo-DGMP + pyrophosphate
5xd1, 5xd2 – MsMuTT 1 + AP5A + ATP
5xd5 – MsMuTT 1 + phosphate + ATP
1vcd, 1vc8 – TtNDX 1 + AP6A – Thermus thermophilus
1vc9 – TtNDX 1 (mutant) + ATP
References
- ↑ McLennan AG. The Nudix hydrolase superfamily. Cell Mol Life Sci. 2006 Jan;63(2):123-43. doi: 10.1007/s00018-005-5386-7. PMID:16378245 doi:http://dx.doi.org/10.1007/s00018-005-5386-7
- ↑ Sheikh S, O'Handley SF, Dunn CA, Bessman MJ. Identification and characterization of the Nudix hydrolase from the Archaeon, Methanococcus jannaschii, as a highly specific ADP-ribose pyrophosphatase. J Biol Chem. 1998 Aug 14;273(33):20924-8. PMID:9694840
- ↑ McLennan AG. The MutT motif family of nucleotide phosphohydrolases in man and human pathogens (review). Int J Mol Med. 1999 Jul;4(1):79-89. PMID:10373642
- ↑ Ranatunga W, Hill EE, Mooster JL, Holbrook EL, Schulze-Gahmen U, Xu W, Bessman MJ, Brenner SE, Holbrook SR. Structural studies of the Nudix hydrolase DR1025 from Deinococcus radiodurans and its ligand complexes. J Mol Biol. 2004 May 21;339(1):103-16. PMID:15123424 doi:http://dx.doi.org/10.1016/j.jmb.2004.01.065
