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Function(s) and Biological Relevance
Inosine-5'-monophosphate dehydrogenase (IMPDH) catalyzes the rate limiting step of the de novo guanine nucleotide biosynthetic pathway. NAD is reduced resulting in IMP converting to Xanthosine monophosphate (XMP). IMPDH is found in organisms that go through the purine biosynthetic pathway, this includes humans.
Broader Implications
Structural highlights and structure-function relationships
Energy Transformation
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