5xa5

Structural highlights

Function

[HMP1_CAEEL] Required for cell migration during body enclosure and cell shape changes during body elongation (PubMed:9531567). Required for proper localization of other junctional components, such as pac-1 (PubMed:25938815).^{[1] [2]} [HMP2_CAEEL] Required for cell migration during body enclosure and cell shape changes during body elongation.^[3]

References

1. ↑ Klompstra D, Anderson DC, Yeh JY, Zilberman Y, Nance J. An instructive role for C. elegans E-cadherin in translating cell contact cues into cortical polarity. Nat Cell Biol. 2015 Jun;17(6):726-35. doi: 10.1038/ncb3168. Epub 2015 May 4. PMID:25938815 doi:http://dx.doi.org/10.1038/ncb3168
2. ↑ Costa M, Raich W, Agbunag C, Leung B, Hardin J, Priess JR. A putative catenin-cadherin system mediates morphogenesis of the Caenorhabditis elegans embryo. J Cell Biol. 1998 Apr 6;141(1):297-308. PMID:9531567
3. ↑ Costa M, Raich W, Agbunag C, Leung B, Hardin J, Priess JR. A putative catenin-cadherin system mediates morphogenesis of the Caenorhabditis elegans embryo. J Cell Biol. 1998 Apr 6;141(1):297-308. PMID:9531567