2lmz

Structural highlights

Function

[CONA_CONIM] Neurotoxin that induces excitatory symptoms in mice following intracranial administration. No symptoms are observed after intraperitoneal and intravenous (tail vein) injections.^[1]

References

1. ↑ Ye M, Khoo KK, Xu S, Zhou M, Boonyalai N, Perugini MA, Shao X, Chi C, Galea CA, Wang C, Norton RS. A helical conotoxin from Conus imperialis has a novel cysteine framework and defines a new superfamily. J Biol Chem. 2012 Apr 27;287(18):14973-83. Epub 2012 Mar 7. PMID:22399292 doi:http://dx.doi.org/10.1074/jbc.M111.334615