PDB ID 6ny0
[DYR21_ECOLX] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
OCA
Categories: Bacillus coli migula 1895 | Dihydrofolate reductase | Large Structures | Berghuis, A M | Yachnin, B J | Antibiotic | Antibiotic resistance | Oxidoreductase | R67 dhfr | Selective inhibitor | Sh3-like barrel