2a28

Structural highlights

Function

[BZZ1_YEAST] Plays a role in endocytosis and trafficking to the vacuole. Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Soulard A, Lechler T, Spiridonov V, Shevchenko A, Shevchenko A, Li R, Winsor B. Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. Mol Cell Biol. 2002 Nov;22(22):7889-906. PMID:12391157
2. ↑ Soulard A, Friant S, Fitterer C, Orange C, Kaneva G, Mirey G, Winsor B. The WASP/Las17p-interacting protein Bzz1p functions with Myo5p in an early stage of endocytosis. Protoplasma. 2005 Oct;226(1-2):89-101. Epub 2005 Oct 20. PMID:16231105 doi:http://dx.doi.org/10.1007/s00709-005-0108-4