6tmf

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Structure of an archaeal ABCE1-bound ribosomal post-splitting complex

Structural highlights

6tmf is a 30 chain structure with sequence from [1] and Thermococcus celer vu 13 = jcm 8558. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, , ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A0A218P4M9_THECE] Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.[HAMAP-Rule:MF_00531] [A0A218P4N5_THECE] With S4 and S12 plays an important role in translational accuracy.[HAMAP-Rule:MF_01307] [A0A218NZW1_THECE] Binds 16S rRNA, required for the assembly of 30S particles.[HAMAP-Rule:MF_01364] [A0A218P4W7_THECE] May be involved in maturation of the 30S ribosomal subunit.[HAMAP-Rule:MF_01474] [A0A218NZT2_THECE] Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.[HAMAP-Rule:MF_01315] [A0A218P3Q8_THECE] Involved in the binding of tRNA to the ribosomes.[HAMAP-Rule:MF_00508][SAAS:SAAS00243318] [A0A218P167_THECE] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.[HAMAP-Rule:MF_00326] [A0A218NZU7_THECE] Binds the lower part of the 30S subunit head.[HAMAP-Rule:MF_01309] [A0A218P4K4_THECE] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.[HAMAP-Rule:MF_00480] [A0A218NZU0_THECE] Located on the platform of the 30S subunit.[HAMAP-Rule:MF_01310] [A0A218P4I2_THECE] With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.[HAMAP-Rule:MF_00403][RuleBase:RU004490] [A0A218NZX3_THECE] One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.[HAMAP-Rule:MF_01345] [A0A218NZT7_THECE] One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.[HAMAP-Rule:MF_01302] [A0A218NZV3_THECE] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.[HAMAP-Rule:MF_01306][SAAS:SAAS00896430] With S5 and S12 plays an important role in translational accuracy.[HAMAP-Rule:MF_01306][SAAS:SAAS00896433]