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Contents

Mitochondrial Calcium Uniporter, E. coli

Introduction

selectivity pore

Disease

Relevance

Calcium signaling

Structural highlights and mechanism

The MCU is a dimer of dimers, described as tetrameric truncated pyramid. The uniporter has only a single strong binding site located in the selectivity pore with specificity for Calcium, near the surface of the inner mitochondrial membrane.[1] [2] [1]

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Madison Summers

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