2kai

From Proteopedia

REFINED 2.5 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF THE COMPLEX FORMED BY PORCINE KALLIKREIN A AND THE BOVINE PANCREATIC TRYPSIN INHIBITOR. CRYSTALLIZATION, PATTERSON SEARCH, STRUCTURE DETERMINATION, REFINEMENT, STRUCTURE AND COMPARISON WITH ITS COMPONENTS AND WITH THE BOVINE TRYPSIN-PANCREATIC TRYPSIN INHIBITOR COMPLEX

spinqualitylabelsall models 2kai, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Structural highlights 2kai is a 3 chain structure with sequence from Bovin and Pig. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Activity: Hydrolase, with EC number and 3.4.21.35 3.4.21.34 and 3.4.21.35 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [KLK_PIG] Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. [BPT1_BOVIN] Inhibits trypsin, kallikrein, chymotrypsin, and plasmin. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Basic Pancreatic Trypsin Inhibitor Kallikrein Contents 1 Structural highlights 2 Function 3 Evolutionary Conservation 4 See Also