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1b8x

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Revision as of 15:56, 30 March 2008 by OCA (Talk | contribs)
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PDB ID 1b8x

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, resolution 2.70Å
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



GLUTATHIONE S-TRANSFERASE FUSED WITH THE NUCLEAR MATRIX TARGETING SIGNAL OF THE TRANSCRIPTION FACTOR AML-1


Overview

A glutathione S-transferase fused with the nuclear matrix targeting signal (GST-NMTS) of AML-1/CBF-alpha2 has been crystallized by the vapor diffusion method using polyethylene glycol (PEG) as the precipitant. The NMTS is a 31-amino-acid signal peptide that can target the AML-1/CBF-alpha2 protein to the nuclear matrix. The crystal belongs to tetragonal space group P43212 with unit cell dimensions a = b = 93.4 A, c = 57.6 A. There is one GST-fusion protein per asymmetric unit. Crystals diffracted to at least 2.7 A and are appropriate for structure determination.

About this Structure

1B8X is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Preliminary crystallographic study of glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription factor AML-1/CBF-alpha2., Tang L, Guo B, van Wijnen AJ, Lian JB, Stein JL, Stein GS, Zhou GW, J Struct Biol. 1998 Sep;123(1):83-5. PMID:9774548

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