This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Protegrin
From Proteopedia
| |||||||||||
3D structures of protegrin
Updated on 08-October-2020
1pg1, 1zy6 – pPRO1 – pig – NMR
2muh - pPRO2 residues 131-146 - NMR
1n5h, 1n5p – pPRO3 cathelin-like domain – NMR
1kwi, 1lxe, 1pfp – pPRO3 cathelin-like domain
2m2z, 2mz6 - pPRO3 residues 131-148 - NMR
6qkf – pPRO4 residues 131-148 - NMR
2nc7 – pPRO5 residues 131-148 - NMR
References
Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes., Fahrner RL, Dieckmann T, Harwig SS, Lehrer RI, Eisenberg D, Feigon J, Chem Biol. 1996 Jul;3(7):543-50. PMID:8807886
- ↑ Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity., Lehrer RI, Barton A, Daher KA, Harwig SS, Ganz T, Selsted ME., J Clin Invest. 1989 Aug;84(2):553-61. PMID: 2668334
- ↑ Susceptibility of Chlamydia trachomatis to protegrins and defensins., Yasin B, Harwig SS, Lehrer RI, Wagar EA., Infect Immun. 1996 Mar;64(3):709-13. PMID: 8641770
- ↑ Membrane channel formation by antimicrobial protegrins., Sokolov Y, Mirzabekov T, Martin DW, Lehrer RI, Kagan BL, Biochim Biophys Acta. 1999 Aug 20;1420(1-2):23-9. PMID:10446287
- ↑ Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity, D A Steinberg, M A Hurst, C A Fujii, A H Kung, J F Ho, F C Cheng, D J Loury, and J C Fiddes, Antimicrob Agents Chemother. 1997 August; 41(8): 1738–1742. PMCID: PMC163996
- ↑ NPG1. EBI QuickGO. http://www.ebi.ac.uk/QuickGO/GProtein?ac=P32194
- ↑ Protein: Protegrin 1 (PG1) from Pig (Sus scrofa). Structural Classification of Proteins. http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.ba.e.b.f.b.html
Created with the participation of Lee Tien.
