This is a default text for your page '. Click above on edit this page' to modify. Be careful with the < and > signs.
You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Function of your Protein
it binds to a host cell (human epithelial cell) to provide a host cell recognition to invade the human cell. In this case, these epithelial adhesions are adhering Candida glabrata to a human epithelial cell.
Biological relevance and broader implications
Candida glabrata is a fungus that is able to infect a human host through the bloodstream. Unfortunately, this is a life-threatening infection for humans. By trying to understand the structure of the epithelial adhesion on the outer surface of the fungus. There could be a possibility of stoping the adhesion from attaching to the host cell and stop host cell recognition altogether. This could help in lowering the high amount of cases that are life-threatening as there are upwards of 29% of cases.
Important amino acids
The type of protein that we are looking at is an adhesion protein, so it does not function as an enzyme. It does not have a catalytic triad within the active site. Though there are some important amino acid residues to highlight as they interact with the ligand (lactose). In the diagram of the protein, we can look to see the red ball stick structures by the ligand are the amino acid residues interacting with the ligand. They are all interacting via hydrogen bonds.
Structural highlights
Some things to note are the
Other important features
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.