This is the 3D structure representation of the Spike glycoprotein
[1] [2].
Function
SARS-Cov-2 utilizes the S-protein to facilitate attachment to host cell surface membranes.
Disease
This protein is related to the SARS-cov-2
Relevance
The S-protein of SARS-CoV-2 expressed by the ORF1b gene is trimeric in structure, where each monomer is 180 kDa in size and has two main subunits, an S1 and an S2 subunit. S1 subunit attaches itself to the host cell angiotensin-converting enzyme 2 (ACE2) transmembrane protein. S2 subunit acts in the fusion process of the S-protein which is done by the cleavage protease transmembrane serine or furin [3]
