1wi5

Structural highlights

Function

[RRP5_HUMAN] Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA.^[1] Involved in the biogenesis of rRNA (By similarity).^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Sweet T, Yen W, Khalili K, Amini S. Evidence for involvement of NFBP in processing of ribosomal RNA. J Cell Physiol. 2008 Feb;214(2):381-8. PMID:17654514 doi:http://dx.doi.org/10.1002/jcp.21204
2. ↑ Sweet T, Yen W, Khalili K, Amini S. Evidence for involvement of NFBP in processing of ribosomal RNA. J Cell Physiol. 2008 Feb;214(2):381-8. PMID:17654514 doi:http://dx.doi.org/10.1002/jcp.21204