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2x36 - Structure of the proteolytic domain of the Human Mitochondrial Lon protease
2x36 is a 6 chain structure with sequence from Human. This domain belongs to the [1] Lon protease family.
Mitochondrial Lon protease is an ATP-dependent serine protease involved in the selective degradation of abnormal proteins. LONP1 situated on chromosome 19 is the nuclear gene encoding mitochondrial Lon protein. The single species of mRNA of this protein is found in the mitochondrial matrix. This protein from human tissues has a molecular mass of 100 kDA.
Function
General structure
Structural highlights
Evolutionary conservation
Disease
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